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Federal Open GRANTS-GOV-362954

Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

National Institutes of Health (NIH) · Competitive · Science & Technology

At a glance

Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed) is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding: $7M total. Eligible applicants: Native American tribal governments (Federally recognized); County governments; Private institutions of higher education; City or township governments; Independent school districts; For profit organizations other than sma. The application deadline is January 29, 2027. Apply via the official listing at www.grants.gov.

Amount
$7M total
Deadline
Jan 29, 2027
Type
Competitive
Status
Open

About this program

The purpose of this notice of funding opportunity (NOFO) is to support a consortium of Translational Centers using Microphysiological Systems (MPS) for Infectious Diseases (TCMID). Recent efforts in the MPS fields are moving towards validation and regulatory use but have not focused upon models studying infectious diseases and testing of medical interventions. The NIH and FDA have recently issued guidance and established initiatives for enhancing use of New Approach Methodologies (NAMs) in research and product development. This includes in vitro systems that allow scientists to model human disease and capture human variability and patient-specific characteristics that will accelerate safer treatments for patients while reducing costs and sparing use of laboratory animals. To meet this need, the Centers will refine well validated human tissue models studying infectious diseases to a level consistent with regulatory qualifications that will promote their adoption for use by product developers, supporting regulatory acceptance.

Who can apply

Native American tribal governments (Federally recognized); County governments; Private institutions of higher education; City or township governments; Independent school districts; For profit organizations other than small businesses; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Public housing authorities/Indian housing authorities; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education. Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

How to apply

Apply through Grants.gov using funding opportunity number RFA-AI-28-012. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.

Apply at official source