At a glance
Selective Precision Targeting (SPoT) is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding: 1500000. Eligible applicants: State governments; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Private institutions of higher education; Small businesses; Native American tribal governmen. Applications are accepted on a rolling basis. Apply via the official listing at www.grants.gov.
- Amount
- $1.5M total
- Deadline
- Rolling
- Type
- Competitive
- Status
- Forecasted
About this program
The National Center for Advancing Translational Science (NCATS) seeks to advance its mission by establishing a new initiative called Selective Precision Targeting (SPoT) to determine a mechanism for precise and on-target therapeutic drug delivery to specific hard-to-reach locations within the human body using microphysiological systems (MPS). Targeted drug-delivery systems, including engineered nanoparticles, extracellular vesicles or focused ultrasound, are methods for delivering medications to a specific area of the body (organ, tissue, or cell) to increase the concentration of the drug in that area. Hard-to-reach locations in the body include the blood–brain barrier, central nervous system, placenta, retina, or a tumor.More specifically, the initiative goals are to:Optimize specific targeting of nanoparticle therapeutics to the target organ/cell of interestAssess biodistribution and off-target effects using a multi-organ microphysiological systemProvide evidence of functional cargo activityDetermine optimal route of administrationGrant authorities that allow the National Center for Advancing Translational Science (NCATS) to forecast this opportunity are as follows: 42 U.S. Code § 287a - Cures Acceleration Network.
Who can apply
State governments; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Private institutions of higher education; Small businesses; Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Public and State controlled institutions of higher education; County governments; Native American tribal organizations (other than Federally recognized tribal governments)
How to apply
Apply through Grants.gov using funding opportunity number FOR-TR-27-003. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
Apply at official sourceRelated grants
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- NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Independent Clinical Trial Not Allowed) NIH · See listing · Jul 12, 2027 Open
- Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional) NIH · Up to $25K · Jun 2, 2027 Open
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