At a glance
NIH Director's Transformative Research Award (R01 Clinical Trial Optional) is a federal competitive grant from National Institutes of Health for the science & technology sector. Eligible applicants: State governments; Independent school districts; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County gove. Applications are accepted on a rolling basis. Apply via the official listing at www.grants.gov.
- Amount
- See listing
- Deadline
- Rolling
- Type
- Competitive
- Status
- Forecasted
About this program
The NIH Director's Transformative Research Award supports individual scientists and research teams pursuing bold, groundbreaking, and unconventional research with the potential to transform science, create new scientific paradigms, establish new clinical approaches, or develop transformative technologies. The Transformative Research Award is part of the NIH Common Fund's High-Risk, High-Reward Research Program.
Who can apply
State governments; Independent school districts; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Public housing authorities/Indian housing authorities; City or township governments; Special district governments; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education. Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to apply
Apply through Grants.gov using funding opportunity number RFA-RM-28-003. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
Apply at official sourceRelated grants
- Inspire Grants for Small Museums (2027) IMLS · $5K–$75K · Nov 13, 2026 Open
- NICHD Small Research Grant Program (R03 Clinical Trial Required) NIH · Up to $50K · Jan 7, 2028 Open
- NIH Research Project Grant (Parent R01 Clinical Trial Required) NIH · See listing · Jan 7, 2028 Open
- Native American Research Centers for Health (NARCH) Planning Grants (R34 - Clinical Trial Not Allowed) NIH · See listing · Jul 7, 2028 Open