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Federal Closing soon GRANTS-GOV-361084

NIH Director’s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)

National Institutes of Health (NIH) · Competitive grant · Science & Technology

At a glance

NIH Director’s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional) is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding: 8000000. Eligible applicants: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Independent school districts; Public and State controlled institutions of higher education; Special distri. The application deadline is September 3, 2026. Apply via the official listing at www.grants.gov.

Amount
$8M total
Deadline
Sep 3, 2026
Type
Competitive
Status
Closing soon

About this program

The NIH Director"s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome; topics may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Director"s Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Who can apply

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Independent school districts; Public and State controlled institutions of higher education; Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; State governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Native American tribal governments (Federally recognized); City or township governments; For profit organizations other than small businesses. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

How to apply

Apply through Grants.gov using funding opportunity number RFA-RM-27-003. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.

Apply at official source