At a glance
Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional) is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding is up to $2M. Eligible applicants: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Special district governments; County governments; Native American tribal governments (Federall. Applications are accepted on a rolling basis. Apply via the official listing at www.grants.gov.
- Amount
- Up to $2M
- Deadline
- Rolling
- Type
- Competitive
- Status
- Forecasted
About this program
The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications that propose translational research hubs with multiple highly integrated components focused on research, capacity building, and community/public health translation for regionally relevant topics related to the health impacts of extreme weather and cumulative exposures, including but not limited to wildfire smoke, extreme heat, flooding, hurricanes, drought, and other climate-related hazards affecting populations at heightened risk across the lifespan. Responsive applications will be led by a multidisciplinary team of investigators with non-academic partners, such as state and local public health departments, community-based organizations, Tribal entities, health care systems, and emergency preparedness agencies. Consortia of multiple institutions are encouraged, particularly those that demonstrate meaningful community engagement and balanced, mutually beneficial partnership structures. Research can be situated at different nodes on the translational research continuum, spanning from fundamental to implementation research with a focus on being problem-based and solutions oriented, and should clearly inform pathways to support implementation, scalability, and measurable public health impact. Award recipients will be expected to collaborate with the HEW Research Coordination and Data Center(s) and other members of the HEW Community of Practice, including participation in data harmonization efforts, shared metrics development, and cross-site dissemination activities. This NOFO will utilize the U54 activity code, that supports specialized centers that function as regional resources for targeted research initiatives, including support for infrastructure development, pilot projects, and partnerships with affected communities throughout the research lifecycle. The U54 is a cooperative agreement that anticipates substantial federal programmatic staff involvement to assist investigators in the achievement of project objectives, including coordination across funded hubs, strategic alignment with NIH priorities, and facilitation of cross-institute collaboration. Grant authorities that allow NIEHS to forecast this opportunity are as follows: 42 USC 285l (NIEHS specific); 42 USC sections 241 (NIH grant authorities).
Who can apply
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Special district governments; County governments; Native American tribal governments (Federally recognized); City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Public and State controlled institutions of higher education; Private institutions of higher education. Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations
How to apply
Apply through Grants.gov using funding opportunity number RFA-ES-28-002. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
Apply at official sourceRelated grants
- NSF Astronomy and Astrophysics Postdoctoral Fellowships NSF · Up to $110K · Oct 15, 2026 Open
- NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Independent Clinical Trial Not Allowed) NIH · See listing · Jul 12, 2027 Open
- Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional) NIH · Up to $25K · Jun 2, 2027 Open
- Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required) NIH · See listing · Jun 7, 2028 Open