At a glance
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed) is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding is up to $350K. Eligible applicants: Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Native America. The application deadline is January 15, 2027. Apply via the official listing at www.grants.gov.
- Amount
- Up to $350K
- Deadline
- Jan 15, 2027
- Type
- Competitive
- Status
- Open
About this program
This funding opportunity is part of a suite of NOFOs within the NIH HEAL Initiative to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal is to encourage initial translational efforts that will support a drug discovery program and advance projects to the point where they meet the entry criteria for the Pain Therapeutics Development Program. The scope will therefore be focused on development of assays to support a distinct testing funnel, screening efforts to identify hits, and initial characterization of hits and potential therapeutic agents (including small molecules, biologics, and natural products).
Who can apply
Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Native American tribal governments (Federally recognized); Independent school districts; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Private institutions of higher education; For profit organizations other than small businesses; Special district governments; State governments; County governments; Public housing authorities/Indian housing authorities. Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
How to apply
Apply through Grants.gov using funding opportunity number RFA-NS-25-023. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
Apply at official sourceRelated grants
- NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) NIH · See listing · Jan 7, 2028 Open
- Native American Research Centers for Health (NARCH) Planning Grants (R34 - Clinical Trial Not Allowed) NIH · See listing · Jul 7, 2028 Open
- Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) NIH · See listing · Jan 7, 2028 Open
- Cannabis Research and Innovation Funding Opportunity (RIFO) Department of Fish and Wildlife · Dependant on number of submissions received, application process, etc. · Rolling Open