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Federal Forecasted GRANTS-GOV-361287

Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)

National Institutes of Health (NIH) · Competitive grant · Science & Technology

At a glance

Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional) is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding: 6000000. Eligible applicants: For profit organizations other than small businesses; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; County governments; C. Applications are accepted on a rolling basis. Apply via the official listing at www.grants.gov.

Amount
$6M total
Deadline
Rolling
Type
Competitive
Status
Forecasted

About this program

The National Institutes of Neurological Disorders and Stroke (NINDS) is interested in supporting research projects proposing the optimization and translational development of genomic and biologic therapeutic candidates for Alzheimer’s Disease-Related Dementias (ADRD). Breakthroughs in genomic and biologic therapies are creating new opportunities to treat, prevent, and potentially modify the course of dementias; however, progress is limited by challenges in delivery, safety, manufacturability, and readiness for clinical testing.This program is intended to support projects across the translational pipeline, from optimization through IND development and early clinical evaluation, for genomic and biologic therapeutic candidates with compelling preclinical evidence. Eligible projects may include activities to refine therapeutic design and manufacturability; establish pharmacology, toxicology, biodistribution, and in vivo efficacy; to generate the full body of data required to support regulatory interactions and IND submissions, and, when appropriate, first-in-human (FIH) clinical studies.The program is aligned with priorities from the ADRD Summits, including acceleration of disease-modifying therapeutic development in frontotemporal degeneration (FTD), Lewy body dementia (LBD), and vascular contributions to cognitive impairment and dementia (VCID). Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

Who can apply

For profit organizations other than small businesses; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; County governments; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Public housing authorities/Indian housing authorities; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized). Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

How to apply

Apply through Grants.gov using funding opportunity number RFA-NS-26-030. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.

Apply at official source