At a glance
Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional) is a federal competitive grant from National Institutes of Health for the science & technology sector. Eligible applicants: County governments; Small businesses; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of high. The application deadline is June 16, 2028. Apply via the official listing at www.grants.gov.
- Amount
- See listing
- Deadline
- Jun 16, 2028
- Type
- Competitive
- Status
- Open
About this program
This notice of funding opportunity (NOFO) uses a R61/R33 Phased Innovation Award activity code to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying substance use disorders (SUD), including fundamental circuitry and behavior relevant to substance use. For projects not requiring a phased research approach, applicants are encouraged to apply under a different funding activity code (e.g., PA-25-305 "Research Project Grant (Parent R01 Clinical Trial Required)" or its subsequent reissue).
Who can apply
County governments; Small businesses; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; City or township governments; For profit organizations other than small businesses; Public housing authorities/Indian housing authorities; Special district governments; State governments; Native American tribal governments (Federally recognized); Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.
How to apply
Apply through Grants.gov using funding opportunity number PAR-27-053. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
Apply at official sourceRelated grants
- NICHD Small Research Grant Program (R03 Clinical Trial Required) NIH · Up to $50K · Jan 7, 2028 Open
- Museum Grants for American Latino History and Culture (2027) IMLS · $5K–$500K · Nov 13, 2026 Open
- Native American Research Centers for Health (NARCH) Planning Grants (R34 - Clinical Trial Not Allowed) NIH · See listing · Jul 7, 2028 Open
- Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional) NIH · See listing · Nov 18, 2026 Open