At a glance
Empire State Development Life Science R&D Tax Credit Buy-Back Grant is a New York state entitlement grant from Empire State Development (ESD) providing up to $500,000 for refundable r&d support for early-stage new york life science companies. Eligible applicants are life science companies under 10 years old with fewer than 100 employees and qualifying r&d expenditures performed in new york state. Applications are accepted on a rolling basis. Apply via esd.ny.gov.
- Amount
- Up to $500K
- Deadline
- Rolling
- Type
- Entitlement
- Status
- Open
About this program
Qualifying early-stage life science companies in New York receive a refundable benefit equal to 15% of in-state R&D spending (20% for companies partnering with New York universities), paid out as an annual grant. Certification is formula-based: companies meeting the statutory definition receive the benefit without competitive review.
Who can apply
Life science companies under 10 years old with fewer than 100 employees and qualifying R&D expenditures performed in New York State.
How to apply
Applications are submitted through the Empire State Development online portal. Register your organization, complete the online application form, and upload a project narrative, budget and supporting documentation before the deadline. Late or incomplete submissions are not reviewed.
Apply at official sourceRelated grants
- NJEDA Catalyst Research & Development Voucher Program NJEDA · Up to $25K · Rolling Open
- MLSC Small Business Matching Grant Program MLSC · Up to $500K · Nov 20, 2026 Open
- TEDCO Maryland Innovation Initiative (MII) Technology Assessment Awards TEDCO · Up to $165K · Rolling Open
- MLSC Bits to Bytes - Data Science for Life Sciences MLSC · $250K–$750K · Oct 8, 2026 Closing soon