At a glance
Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding is up to $3M. Eligible applicants: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; State governments; Nonprofits having a 501(c)(3) status with the IRS, other than ins. The application deadline is August 21, 2028. Apply via the official listing at www.grants.gov.
- Amount
- Up to $3M
- Deadline
- Aug 21, 2028
- Type
- Competitive
- Status
- Open
About this program
The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. This NOFO will utilize the UG3/UH3 activity code.
Who can apply
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; State governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Small businesses; Public housing authorities/Indian housing authorities; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; County governments; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); City or township governments. Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.
How to apply
Apply through Grants.gov using funding opportunity number PAR-25-446. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
Apply at official sourceRelated grants
- NSF Astronomy and Astrophysics Postdoctoral Fellowships NSF · Up to $110K · Oct 15, 2026 Open
- NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Independent Clinical Trial Not Allowed) NIH · See listing · Jul 12, 2027 Open
- Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional) NIH · Up to $25K · Jun 2, 2027 Open
- Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required) NIH · See listing · Jun 7, 2028 Open