At a glance
Assessing the Feasibility of Incorporating Mechanisms in Multi-site Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R33 Clinical Trial Required) is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding is up to $500K. Eligible applicants: Native American tribal governments (Federally recognized); City or township governments; Public housing authorities/Indian housing authorities; Private institutions of higher education; Others (see text field entitled "A. The application deadline is November 16, 2029. Apply via the official listing at www.grants.gov.
- Amount
- Up to $500K
- Deadline
- Nov 16, 2029
- Type
- Competitive
- Status
- Open
About this program
The National Center for Complementary and Integrative Health (NCCIH) announces this Notice of Funding Opportunity (NOFO) to solicit applications for multi-site feasibility trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) to reproduce and translate mechanisms of emotional well-being (EWB) into large-scale clinical trials that advance our understanding of whole person health. These early-phase multi-site trials are essential for 1) demonstrating that the mind and body intervention can be delivered with fidelity across sites; 2) demonstrating reproducibility and rigor in engaging targeted mechanisms of EWB by the mind and body intervention across sites; 3) assessing feasibility of participant recruitment and retention, as well as randomization; 4) assessing feasibility of collecting comprehensive clinical (whole person health restoration) and mechanistic (EWB) data across sites; and 5) exploring correlations between changes in mechanistic targets and clinical outcome measurements pooled across sites. By laying this groundwork, studies supported under this NOFO will advance the science of whole person health and prepare the field for rigorous clinical trials and mechanistic mediation analysis with the potential to improve the health and well-being of all Americans.
Who can apply
Native American tribal governments (Federally recognized); City or township governments; Public housing authorities/Indian housing authorities; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; State governments; Public and State controlled institutions of higher education. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
How to apply
Apply through Grants.gov using funding opportunity number PAR-28-091. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
Apply at official sourceRelated grants
- RESTORE Act Direct Component - Non-Construction Activities USDOT · Up to $120.2M · Oct 31, 2027 Open
- FY 2026 - 2028 Broad Agency Announcement (BAA), National Ocean Service DOC · Up to $100 · Sep 30, 2028 Open
- Landscape Scale Restoration Grant Program for Tribes USDA · $100K–$300K · Jan 26, 2027 Open
- FY 2027 Crash Causal Factors Program DOT · $25K–$500K · Dec 28, 2026 Open